Publications (2014 – Present)

2020

2020

Polymer Domains Control Diffusion in Protein–Polymer Conjugate Biosensors. J.M. Paloni and B. D. Olsen. ACS Appl. Polym. Mater. 2020.

Fracture of Polymer Networks Containing Topological Defects. A. Arora, T.S. Lin, H. K. Beech, H. Mochigase, R. Wang, and B. D. Olsen. Macromolecules 2020 53, 7346–7355.

Understanding the molecular origin of shear thinning in associative polymers through quantification of bond dissociation under shear. I. M. Rasid, J. Ramirez, B.D. Olsen, and N Holten-Andersen. Physical Review Materials 2020, 4, 055602.

Secondary structure drives self-assembly in weakly segregated globular protein–rod block copolymers. H. Yao*, K. Sheng*, J. Sun, S. Yan, Y. Hou, H. Lu, and B.D. Olsen. Polym. Chem. 2020, 11, 3032-3045. *Equal Contributions

Glycoprotein Mimics with Tunable Functionalization through Global Amino Acid Substitution and Copper Click Chemistry. B.M. Seifried*, W. Qi*, Y.J. Yang, D.J. Mai, W. Puryear, J.A. Runstadler, G. Chen, and B.D. Olsen. Bioconjugate Chem. 2020, 31, 554-566. *Equal Contributions

Coiled-Coil Domains for Self-Assembly and Sensitivity Enhancement of Protein–Polymer Conjugate Biosensors. J. Paloni and B.D. Olsen. ACS Appl. Polym. Mater. 2020, 2, 1114-1123.

Molecular anisotropy and rearrangement as mechanisms of toughness and extensibility in entangled physical gels. C. E. R. Edwards*, D. J. Mai*, S. Tang, and B.D. Olsen. Physical Review Materials 4, 015602. *Equal Contributions

2019

2019

Protein–Polymer Block Copolymer Thin Films for Highly Sensitive Detection of Small Proteins in Biological Fluids. J. Paloni, X. Dong, and B.D. Olsen. ACS Sens. 2019, 4, 2869-2878.

BigSMILES: A Structurally-Based Line Notation for Describing Macromolecules. T.-S. Lin, C.W. Coley, H. Mochigase, H.K. Beech, W. Wang, Z. Wang, E. Woods, S.L. Craig, J.A. Johnson, J.A. Kalow, K.F. Jensen, and B.D. Olsen. ACS Central Science 2019, 5, 1523-1531.

Predicting Protein–Polymer Block Copolymer Self-Assembly from Protein Properties. A. Huang, J.M. Paloni, A. Wang, A.C. Obermeyer, H.V. Sureka, H. Yao, B.D. Olsen. Biomacromolecules 2019, 20, 31713-3723.

SANS partial structure factor analysis for determining protein–polymer interactions in semidilute solution. A. Huang,* H. Yao,* and B.D. Olsen. Soft Matter 2019, 15, 7350-7359. *Equal contributions. [Cover.]

Catalytic Biosensors from Complex Coacervate Core Micelle (C3M) Thin Films. H.V. Sureka, A.C. Obermeyer, R.J. Flores, and B.D. Olsen. ACS Applied Materials and Interfaces 2019, 11, 32354-32365.

Non-isocyanate urethane linkage formation using l-lysine residues as amine sources. C. Peixoto, A.M.S. Soares, A. Araujo, B.D. Olsen, and A.V. Machado. Amino Acids 2019, 1-13.

Protein Purification by Ethanol-Induced Phase Transitions of the Elastin-like Polypeptide (ELP). C.E. Mills,* E. Ding,* and B.D. Olsen. Industrial & Engineering Chemistry Research 2019, Article ASAP. *Equal contributions.

Extending the Phantom Network Theory to Account for Cooperative Effect of Defects. T.-S. Lin, R. Wang, J.A. Johnson, and B.D. Olsen. Macromolecular Symposia 2019, 385, 1900010.

Cononsolvency of Elastin-like Polypeptides in Water/Alcohol Solutions. C.E. Mills, E. Ding, and B.D. Olsen. Biomacromolecules 2019, 20, 2167.

Systemically Administered Hemostatic Nanoparticles for Identification and Treatment of Internal Bleeding. M. Gkikas, T. Peponis, T. Mesar, C. Hong, R.K. Avery, E. Roussakis, H.-J. Yoo, A. Parakh, M. Patino, D.V. Sahani, M.T. Watkins, R. Oklu, C.L. Evans, H. Albadawi, G. Velmahos, and B.D. Olsen. ACS Biomaterials Science & Engineering 2019, 5, 2563.

Hydrophobic and Bulk Polymerizable Protein-Based Elastomers Compatibilized with Surfactants. W.Y. Chan, E.J. King, and B.D. Olsen. ACS Sustainable Chemistry and Engineering 2019, 7, 9103.

Preparation and Characterization of Whey Protein-Based Polymers Produced from Residual Dairy Streams. B. Chalermthai, W.Y. Chan, J.-R. Bastidas-Oyanedel, H. Taher, B.D. Olsen, and J.E. Schmidt. Polymers 2019, 11, 722.

Plasma technology as a tool to decrease the sensitivity to water of fish protein films for food packaging. V.P. Romani, B.D. Olsen, M.P. Collares, J.R.M. Oliveira, C. Prentice, and V.G. Martins. Food Hydrocolloids 2019, 94, 210-216.

Topology effects on protein–polymer block copolymer self-assembly. T. Suguri and B.D. Olsen. Polymer Chemistry 2019, 10, 1751-1761.

Revisiting the Elasticity Theory for Real Gaussian Phantom Networks. T.-S. Lin, R. Wang, J. Johnson, and B.D. Olsen. Macromolecules 2019, 52, 1685–1694.

2018

2018

Polymethacrylamide and Carbon Composites that Grow, Strengthen, and Self-Repair Using Ambient Carbon Dioxide Fixation. S.Y. Kwak, J.P. Giraldo, T.T.S. Lew, M.H. Wong, P. Liu, Y.J. Yang, V.B. Koman, M.K. McGee, B.D. Olsen, and M.S. Strano. Advanced Materials 2018, 1804037.

Green fluorescent proteins engineered for cartilage-targeted drug delivery: Insights for transport into highly charged avascular tissues. Y. Krishnan, H.A. Rees, C.P. Rossitto, S.-E. Kim, H.-H.K. Hung, E.H. Frank, B.D. Olsen, D.R. Liu, P.T. Hammond, A.J. Grodzinsky. Biomaterials 2018, 183, 218-233.

Nucleopore-Inspired Polymer Hydrogels for Selective Biomolecular Transport. Y.J. Yang,* D.J. Mai,* T. Dursh, and B.D. Olsen. Biomacromolecules 2018, 19, 3905-3916. *Equal contributions.

Improved Ordering in Low Molecular Weight Protein–Polymer Conjugates Through Oligomerization of the Protein Block. J.M. Paloni, E.A. Miller, H.D. Sikes, and B.D. Olsen. Biomacromolecules 2018, 19, 3814-3824.

High-velocity micro-particle impact on gelatin and synthetic hydrogel. D. Veysset, S.E. Kooi, A.A. Maznev, S. Tang, A.S. Mijailovic, Y.J. Yang, K. Geiser, K.J. Van Vliet, B.D. Olsen, and K.A. Nelson. Journal of the Mechanical Behavior of Biomedical Materials 2018, 86, 71-76.

Techno-Economic Analysis for Producing Novel, Bio-Derived Elastomers With Modified Algal Proteins as a Reinforcing Agent. T. Bochenski, W.Y. Chan, B.D. Olsen, and J.E. Schmidt. Algal Research 2018, 33, 337-344.

Advancing Polymer Science by Revisiting Known Plastics. B.D. Olsen and B.W. Boudouris. Chem 2018, 4, 927-930.

Elastin-like polypeptide (ELP) charge influences self-assembly of ELP-mCherry fusion proteins. C.E. Mills, Z. Michaud, and B.D. Olsen. Biomacromolecules 2018, 19, 2517–2525.

Multi-Functional, High Molecular Weight, Post-Translationally Modified Protein Brushes Through Oxidative Cysteine Coupling and Tyrosine Modification. B. Seifried, J. Cao, and B.D. Olsen. Bioconjugate Chemistry 2018, 29, 1876–1884.

Influence of End-Block Dynamics on Deformation Behavior of Thermoresponsive Elastin-like Polypeptide Hydrogels. M.K. Sing, W.R. Burghardt, and B.D. Olsen. Macromolecules, 2018, 51, 2951–2960.

A Molecular Explanation for Anomalous Diffusion in Supramolecular Polymer Networks. J. Ramirez, T.J. Dursch, and B.D. Olsen. Macromolecules 2018, 51, 2517–2525.

Counting Secondary Loops is Required for Accurate Prediction of End-Linked Polymer Network Elasticity. J. Wang, T.-S. Lin, Y. Gu, R. Wang, B.D. Olsen, and J.A. Johnson. ACS Macro Letters 2018, 7, 244-249.

Topological Structure of Networks Formed from Symmetric Four-Arm Precursors. T.-S. Lin, R. Wang, J.A. Johnson, and B.D. Olsen. Macromolecules, 2018, 51, 1224–1231.

Engineering Elastin-like Polypeptide-Poly(ethylene glycol) Multiblock Physical Networks. A. Araujo, B.D. Olsen, and A.V. Machado. Biomacromolecules 2018, 19, 329–339.

Effects of pH modification in proteins from fish (Whitemouth croaker) and their application in food packaging films. V.P. Romani, A.V. Machado, B.D. Olsen, and V.G. Martins. Food Hydrocolloids 2018, 74, 307-314.

2017

2017

Kinetic Monte Carlo Simulation for Quantification of the Gel Point of Polymer Networks. R. Wang, T.-S. Lin, J.A. Johnson, and B.D. Olsen. ACS Macro Letters 2017, 6, 1414–1419.

Mechanical response of transient telechelic networks with many-part stickers. M.K. Sing, J. Ramirez, and B.D. Olsen. Journal of Chemical Physics 2017, 147, 194902.

Structure and Rheology of Dual-Associative Protein Hydrogels Under Nonlinear Shear Flow. M.K. Sing, M.J. Glassman, X.T. Voronay-Ruggles, W.R. Burghardt, and B.D. Olsen. Soft Matter 2017, 13, 8511-8524.

Peptide Domains as Reinforcement in Protein-Based Elastomers. W.Y. Chan, T. Bochenski, J.E. Schmidt, and B.D. Olsen. ACS Sustainable Chemistry and Engineering 2017, 5, 8568–8578.

Artificially Engineered Protein Polymers. Y.J. Yang, A.L. Holmberg, and B.D. Olsen. Annual Review of Chemical and Biomolecular Engineering 2017, 8, 549-575.

Self-Assembly of Poly(vinylpyridine-b-oligo(ethylene glycol) methyl ether methacrylate) Diblock Copolymer. C.R. Stewart-Sloan, R. Wang, M.K. Sing, and B.D. Olsen. Journal of Polymer Science Part B: Polymer Physics 2017, 55, 1181–1190.

Semibatch Monomer Addition as a General Method to Tune and Enhance the Mechanics of Polymer Networks via Loop-Defect Control. Y. Gu, K. Kawamoto, M. Zhong, M. Chen, M.J.A. Hore, A.M. Jordan, L.T.J. Korley, B.D. Olsen, and J. Johnson. Proceedings of the National Academy of Sciences of the United States of America 2017, in press. MIT News.

Selective biomolecular separation system inspired by the nuclear pore complex and nuclear transport. M. Kim, W. Chan, B.S. Souza, B.D. Olsen. Molecular Systems Design & Engineering 2017, 2, 149-158.

Odd-Even Effect of Junction Functionality on the Topology and Elasticity of Polymer Networks. R. Wang, J.J. Johnson and B.D. Olsen. Macromolecules 2017, 50, 2556–2564.

Hydrogels that Actuate Selectively in Response to Organophosphates. M. Gkikas, R.K. Avery, C.E. Mills, R. Nagarajan, E. Wilusz, and B.D. Olsen. Advanced Functional Materials 2017, 27, 1602784.

2016

2016

Material Properties of the Cyanobacterial Reserve Polymer Multi-L-Arginyl-Poly-L-Aspartate (Cyanophycin). N.A. Khlystov, W.Y. Chan, A.M. Kunjapur, W. Shi, K.L.J. Prather, and B.D. Olsen. Polymer 2016, 109, 238–245.

Complex Coacervate Core Micelles for the Dispersion and Stabilization of Organophosphate Hydrolase in Organic Solvents. C.E. Mills, A. Obermeyer, X. Dong, E. Kizilay, J. Walker, and B.D. Olsen. Langmuir 2016, 32, 13367–13376.

Three-Dimensional Ordered Antibody Arrays Through Self-Assembly of Antibody-Polymer Conjugates. X. Dong, A. Obermeyer, and B.D. Olsen. Angewandte Chemie 2016, 56, 1273-1277.

Classical Challenges in the Physical Chemistry of Polymer Networks and the Design of New Materials. R. Wang, M.K. Sing, R. K. Avery, B.S. Souza, M. Kim, and B.D. Olsen. Accounts of Chemical Research 2016, 49, 2786–2795.

Relaxation Processes in Supramolecular Metallogels Based on Histidine–Nickel Coordination Bonds. S. Tang and B.D. Olsen. Macromolecules 2016, 49, 9163–9175.

An Injectable Shear-Thinning Biomaterial for Endovascular Embolization. R.K. Avery, H. Albadawi, M. Akbari, Y. S. Zhang, M.J. Duggan, D. V. Sahani, B.D. Olsen, A. Khademhosseini, and R. Oklu. Science Translational Medicine 2016, 8, pp. 365ra156. [Cover.]

Kinetic Effects on Self‐Assembly and Function of Protein–Polymer Bioconjugates in Thin Films Prepared by Flow Coating. D. Chang, A. Huang, and B.D. Olsen. Macromolecular Rapid Communications 2016, 38, 1600449.

Quantifying the impact of molecular defects on polymer network elasticity. M. Zhong, R. Wang, K. Kawamoto, B.D. Olsen, and J.A. Johnson. Science 2016, 353 (6305), 1264-1268. (MIT News Article)

Self-Diffusion of Associating Star-Shaped Polymers. S. Tang, A. Habicht, S. Li, S. Seiffert, and B.D. Olsen. Macromolecules 2016, 49, 5599-5608.

The Effect of Protein Electrostatic Interactions on Globular Protein–Polymer Block Copolymer Self-Assembly. C.N. Lam, H. Yao, and B.D. Olsen. Biomacromolecules 2016, 17, 2820–2829.

Complex Coacervation of Supercharged Proteins With Polyelectrolytes. A.C. Obermeyer, C.E. Mills, X. Dong, and B.D. Olsen. Soft Matter 2016, 12, 3570-3581.

Self-Assembly of Differently Shaped Protein-Polymer Conjugates Through Modification of the Bioconjugation Site. A. Huang and B.D. Olsen. Macromolecular Rapid Communications 2016, 15, 1268-1274.

Self-Assembly of Protein-Zwitterionic Polymer Bioconjugates Into Nanostructured Materials. D. Chang and B.D. Olsen. Polymer Chemistry 2016, 7, 2410-2418.

Biosynthesis of poly(glycolate-co-lactate-co-3-hydroxybutyrate) from glucose by metabolically engineered Escherichia coli. Z.-J. Li, K. Qiao, W. Shi, B. Pereira, H. Zhang, B.D. Olsen, and G.
Stephanopoulos. Metabolic Engineering 2016, 35, 1-8.

Antiviral Agents from Multivalent Presentation of Sialyl Oligosaccharides on Brush Polymers. S. Tang, W. Puryear, B. Seifried, X. Dong, J. Runstadler, K. Ribbeck, and B.D. Olsen. ACS Macro Letters 2016, 5, 413-418.

Effect of ELP Sequence and Fusion Protein Design on Concentrated Solution Self-Assembly. G. Qin, P. Perez, C.E. Mills, and B.D. Olsen. Biomacromolecules 2016, 17, 928-934.

Universal Cyclic Topology in Polymer Networks. R. Wang, A. Alexander-Katz, J.A. Johnson,
and B.D. Olsen. Physical Review Letters 2016, 116, 188302

Counting Primary Loops in Tetra and Mixed Functionality Click Hydrogels. K. Kawamoto, M. Zhong, R. Wang, B.D. Olsen, and J.A. Johnson. Macromolecules 2016, 48 (24), 8980–8988.

Thermoresponsive and Mechanical Properties of Highly Concentrated Aqueous Poly(L-proline) Solutions. M. Gkikas, R.K. Avery, and B.D. Olsen. Biomacromolecules 2016,17 (2), 399–406.

Toughening of Thermoresponsive Arrested Networks of Elastin-Like Polypeptides to Engineer Biocompatible Tissue Scaffolds. M.J. Glassman, R.K. Avery, A. Khademhosseini, and B.D. Olsen. Biomacromolecules 2016, 17 (2), 415-426.

2015

2015

Arrested Phase Separation of Elastin-Like Polypeptide Solutions Yields Stiff, Thermoresponsive Gels. M.J. Glassman and B.D. Olsen. Biomacromolecules 2015, 16 (12), 3762–3773.

The Shape of Protein-Polymer Conjugates in Dilute Solution. C.N. Lam, D. Chang, M. Wang, W.-R. Chen, and B.D. Olsen. J. Poly. Sci. A Polymer Chemistry 2015, 54, 292-302.

A Highly Elastic and Rapidly Crosslinkable Elastin-Like Polypeptide-Based Hydrogel for Biomedical Applications. Y.-N. Zhang, R.K. Avery, Q. Vallmajo-Martin, A. Assman, A. Vegh, A. Memic, B.D. Olsen, N. Annabi, and A. Khademhosseini. Advanced Functional Materials 2015, 25, 4814-4826.

Crossover Between Activated Reptation and Arm Retraction Mechanisms in Entangled Rod-Coil Block Copolymers. M. Wang, A.E. Likhtman, and B.D. Olsen. Journal of Chemical Physics 2015, 143, 184904.

Anomalous Self-Diffusion and Sticky Rouse Dynamics in Associative Protein Hydrogels. S. Tang, M. Wang, and B.D. Olsen. Journal of the American Chemical Society 2015, 137, 3946-3957.

Artificially Engineered Protein Hydrogels Adapted From the Nucleoporin Nsp1 for Selective Biomolecular Transport. M. Kim, W.G. Chen, M.J. Glassman, J.-W. Kang, K. Ribbeck, and B.D. Olsen. Advanced Materials 2015, 27, 4207-4212.

Scattering from Colloid-Polymer Conjugates with Excluded Volume Effect. X. Li, C.N. Lam, L.E. Sanchez-Diaz, G. Smith, B.D. Olsen, and W. Chen. ACS Macro Letters 2015, 4, 165-170.

End Block Design Modulates the Assembly and Mechanics of Thermoresponsive, Dual-Associative Protein Gels. M.J. Glassman and B.D. Olsen. Macromolecules 2015, 48, 1832- 1842.

Self-Diffusion and Constraint Release in Isotropic Entangled Rod-Coil Block Copolymers. M. Wang, K. Timachova, and B.D. Olsen. Macromolecules 2015, 48, 3121-3129.

Tube Curvature Slows Motion of Rod-Coil Block Copolymers Through Activated Reptation. M. Wang, A.E. Likhtman, and B.D. Olsen. ACS Macro Letters 2015, 4, 242-246.

Highly Active Biocatalytic Coatings from Protein-Polymer Diblock Copolymers. A. Huang, G. Qin, and B.D. Olsen. ACS Applied Materials and Interfaces 2015, 7, 14660-14669.

Synthesis and Application of Protein-Containing Block Copolymers. A.C. Obermeyer and B.D. Olsen. ACS Macro Letters 2015, 4, 101-110.

Topological Effects on Globular Protein-ELP Fusion Block Copolymer Self-Assembly. G. Qin, M.J. Glassman, C.N. Lam, D. Chang, E. Schiable, A. Hexemer, and B.D. Olsen. Advanced Functional Materials 2015, 25, 729-738.

Chain Configurations and Rate-Dependent Rheological Properties in Transient Networks. M.K. Sing, Z.G. Wang, G.H. McKinley, and B.D. Olsen. Soft Matter 2015, 11, 2085-2096.

2014

2014

Responsive Block Copolymer Photonics Triggered by Protein-Polyelectrolyte Coacervation. Y. Fan, S. Tang, E.L. Thomas, and B.D. Olsen. ACS Nano 2014, 8, 11467-11473.

Kinetics of Magnetic Field-Induced Orientational Ordering in Block Copolymer/Superparamagnetic Nanoparticle Composites. V. Raman, T.A. Hatton, and B.D. Olsen. Macromolecular Rapid Communications 2014, 35, 2005-2011.

Controlling Topological Entanglement in engineered Protein Hydrogels with a Variety of Thiol Coupling Chemistries. S. Tang and B.D. Olsen. Frontiers in Chemistry 2014, 2, 23.

Effect of Polymer Chemistry on Globular Protein-Polymer Block Copolymer Self-Assembly. D. Chang, C.N. Lam, and B.D. Olsen. Polymer Chemistry 2014, 5, 4884-4895.

Protonation-Induced Microphase Separation in Thin Films of a Polyelectrolyte-Hydrophilic Diblock Copolymer. C.R. Stewart-Sloan and B.D. Olsen. ACS Macro Letters 2014, 3, 410-414.

Defects, Solvent Quality, and Photonic Response in Lamellar Block Copolymer Gels. Y. Fan, J.J. Walish, S. Tang, B.D. Olsen, and E.L. Thomas. Macromolecules 2014, 47, 1130-1136

Coil fraction-dependent phase behaviour of a model globular protein–polymer diblock copolymer. C.S. Thomas and B.D. Olsen. Soft Matter 2014, 10, 3093-3102.

45. Shear-Thinning Nanocomposite Hydrogels for the Treatment of Hemorrhage. A.K. Gaharwar, R.K. Avery, G. McKinley, A. Khademhosseini, and B.D. Olsen. ACS Nano 2014, 8, 9833-9842.

Crossover Experiments Applied to Network Formation Reactions: Improved Strategies for Counting Elastically Inactive Molecular Defects in PEG Gels and Hyperbranched Polymers. H. Zhou, E.-M. Schön, M. Wang, M. J. Glassman, J. Liu, M. Zhong, D. D. Díaz, B. D. Olsen, and J. J. Johnson. JACS, 2014, 136, 9464-9470.

The Nature of Protein Interactions Governing Globular Protein-Polymer Block Copolymer Self-Assembly. C. N. Lam, M. Kim, C. S. Thomas, D. Chang, G. E. Sanoja, C. U. Okwara, and B. D. Olsen. Biomacromolecules, 2014, 15, 1248-1258.

Enhanced activity and stability of organophosphorus hydrolase via interaction with an amphiphilic polymer. M. Kim, M. Gkikas, A. Huang, J. W. Kang, N. Suthiwangcharoen, R. Nagarajan, and B. D. Olsen. Chemical Communications, 2014, 50, 5345-5348.

Oxidatively Responsive Chain Extension to Topologically Entangle Artificially Engineered Protein Hydrogels. S. Tang, M. J. Glassman, S. Li, S. Socrate, and B. D. Olsen. Macromolecules, 2014, 47, 791-799.